Rapid Fluorometric Diagnostic Systems

 

 

Who We Are

Since the early 1950’s, microbiologists have been studying and utilizing enzymes as a method of detecting bacteria.  They discovered specificity of enzymes to microorganisms, however, most companies stopped using enzyme methods, and switched to antigen/antibody or NAAT technologies in the 1970’s and 1980’s.   

 

FluoroVei LLC, however, has maintained its research for almost 30 years, and has discovered specific bacterial enzymes for a host of microorganisms.  Over the years, FluoroVei has developed its proprietary substrates which identify and link to the specific

 

Bacterial Enzymes (light green)

 

 enzymes.  Other diagnostic systems must find the bacteria cell itself, or replicate DNA utilizing a PCR/NAAT system, which will take, in most cases, more than a day to obtain results from the time of sample collection.  In the case of the FluoroQuik system, a bacteria can be producing thousands of molecules of an enzyme which increases the odds and time of being detected at a much faster rate than  any other method of detection.

 

FluoroQuik utilizes proprietary fluorogenic substrates which, when hydrolyzed by a specific enzyme (during peptide hydrolysis), produces a fluorescence which is read by the fluorometer. The numerical readings on the fluorometer are the picomoles of  fluorescence from the reaction of the substrate with the enzyme detected in the sample.  The foundation for FluoroQuik’s success is the fact that the technology is based on the detection of specific enzymes produced by specific microorganisms or bacteria.